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α(S1)-Casein-Loaded Proteo-liposomes as Potential Inhibitors in Amyloid Fibrillogenesis: In Vivo Effects on a C. elegans Model of Alzheimer’s Disease

[Image: see text] According to the amyloid hypothesis, in the early phases of Alzheimer’s disease (AD), small soluble prefibrillar aggregates of the amyloid β-peptide (Aβ) interact with neuronal membranes, causing neural impairment. Such highly reactive and toxic species form spontaneously and trans...

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Detalles Bibliográficos
Autores principales: Paterna, Angela, Santonicola, Pamela, Di Prima, Giulia, Rao, Estella, Raccosta, Samuele, Zampi, Giuseppina, Russo, Claudio, Moran, Oscar, Manno, Mauro, Di Schiavi, Elia, Librizzi, Fabio, Carrotta, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623563/
https://www.ncbi.nlm.nih.gov/pubmed/37847529
http://dx.doi.org/10.1021/acschemneuro.3c00239