Development of a PNGase Rc Column for Online Deglycosylation of Complex Glycoproteins during HDX-MS

[Image: see text] Protein glycosylation is one of the most common PTMs and many cell surface receptors, extracellular proteins, and biopharmaceuticals are glycosylated. However, HDX-MS analysis of such important glycoproteins has so far been limited by difficulties in determining the HDX of the prot...

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Detalles Bibliográficos
Autores principales: Lambert, Thomas, Gramlich, Marius, Stutzke, Luisa, Smith, Luke, Deng, Dingyu, Kaiser, Philipp D., Rothbauer, Ulrich, Benesch, Justin L. P., Wagner, Cornelia, Koenig, Maximiliane, Pompach, Petr, Novak, Petr, Zeck, Anne, Rand, Kasper D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623573/
https://www.ncbi.nlm.nih.gov/pubmed/37756257
http://dx.doi.org/10.1021/jasms.3c00268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623573/
https://www.ncbi.nlm.nih.gov/pubmed/37756257
http://dx.doi.org/10.1021/jasms.3c00268

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