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GHB toxicokinetics and renal monocarboxylate transporter expression are influenced by the estrus cycle in rats

BACKGROUND: The illicit use and abuse of gamma-hydroxybutyric acid (GHB) occurs due to its sedative/hypnotic and euphoric effects. Currently, there are no clinically available therapies to treat GHB overdose, and care focuses on symptom treatment until the drug is eliminated from the body. Proton- a...

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Detalles Bibliográficos
Autores principales: Wei, Hao, Cao, Jieyun, Fallert, Tyler, Yeo, Su, Felmlee, Melanie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623699/
https://www.ncbi.nlm.nih.gov/pubmed/37919807
http://dx.doi.org/10.1186/s40360-023-00700-y