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Targeting the hedgehog pathway in MET mutation cancers and its effects on cells associated with cancer development

The mutation of MET plays a crucial role in the initiation of cancer, while the Hedgehog (Hh) pathway also plays a significant role in cell differentiation and the maintenance of tumor stem cells. Conventional chemotherapy drugs are primarily designed to target the majority of cell populations withi...

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Detalles Bibliográficos
Autores principales: Du, Yifan, Sun, Huimin, Shi, Zhiyuan, Sui, Xiuyuan, Liu, Bin, Zheng, Zeyuan, Liu, Yankuo, Xuan, Zuodong, Zhong, Min, Fu, Meiling, Bai, Yang, Zhang, Qian, Shao, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623711/
https://www.ncbi.nlm.nih.gov/pubmed/37919751
http://dx.doi.org/10.1186/s12964-023-01333-8