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Targeting the hedgehog pathway in MET mutation cancers and its effects on cells associated with cancer development
The mutation of MET plays a crucial role in the initiation of cancer, while the Hedgehog (Hh) pathway also plays a significant role in cell differentiation and the maintenance of tumor stem cells. Conventional chemotherapy drugs are primarily designed to target the majority of cell populations withi...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623711/ https://www.ncbi.nlm.nih.gov/pubmed/37919751 http://dx.doi.org/10.1186/s12964-023-01333-8 |