Acetylcysteine increases sensitivity of ceftazidime-avibactam–resistant enterobacterales with different enzymatic resistance to ceftazidime-avibactam in vitro and in vivo

BACKGROUND: Ceftazidime-avibactam (CZA) improves treatment outcomes for infections caused by carbapenem-resistant organisms, but has led to serious bacterial resistance. Acetylcysteine (NAC) is an approved medication that protects the respiratory tract through antioxidant and anti-inflammatory effec...

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Detalles Bibliográficos
Autores principales: Huang, Zeyu, Han, Yijia, Zhang, Xiaotuan, Sun, Yao, Lin, Yuzhan, Feng, Luozhu, Zhou, Tieli, Wang, Zhongyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623744/
https://www.ncbi.nlm.nih.gov/pubmed/37923985
http://dx.doi.org/10.1186/s12866-023-03068-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623744/
https://www.ncbi.nlm.nih.gov/pubmed/37923985
http://dx.doi.org/10.1186/s12866-023-03068-5

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