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Acetylcysteine increases sensitivity of ceftazidime-avibactam–resistant enterobacterales with different enzymatic resistance to ceftazidime-avibactam in vitro and in vivo
BACKGROUND: Ceftazidime-avibactam (CZA) improves treatment outcomes for infections caused by carbapenem-resistant organisms, but has led to serious bacterial resistance. Acetylcysteine (NAC) is an approved medication that protects the respiratory tract through antioxidant and anti-inflammatory effec...
Autores principales: | Huang, Zeyu, Han, Yijia, Zhang, Xiaotuan, Sun, Yao, Lin, Yuzhan, Feng, Luozhu, Zhou, Tieli, Wang, Zhongyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623744/ https://www.ncbi.nlm.nih.gov/pubmed/37923985 http://dx.doi.org/10.1186/s12866-023-03068-5 |
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