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Sufficient Cav-1 levels in the endothelium are critical for the maintenance of the neurovascular unit in the retina

BACKGROUND: Caveolin-1 (Cav-1) is a pivotal protein in the plasma membrane. Studies on homozygous Cav-1 deficient mice revealed that Cav-1 is essential for endothelial function and angiogenesis in the retina. However, whether a reduction in Cav-1 content hampers the neurovascular unit (NVU) in the r...

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Detalles Bibliográficos
Autores principales: Wang, Yixin, Halawa, Mahmoud, Chatterjee, Anupriya, Eshwaran, Rachana, Qiu, Yi, Wibowo, Yohanes Cakrapradipta, Pan, Jianyuan, Wieland, Thomas, Feng, Yuxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623831/
https://www.ncbi.nlm.nih.gov/pubmed/37923999
http://dx.doi.org/10.1186/s10020-023-00749-9