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Sufficient Cav-1 levels in the endothelium are critical for the maintenance of the neurovascular unit in the retina
BACKGROUND: Caveolin-1 (Cav-1) is a pivotal protein in the plasma membrane. Studies on homozygous Cav-1 deficient mice revealed that Cav-1 is essential for endothelial function and angiogenesis in the retina. However, whether a reduction in Cav-1 content hampers the neurovascular unit (NVU) in the r...
Autores principales: | Wang, Yixin, Halawa, Mahmoud, Chatterjee, Anupriya, Eshwaran, Rachana, Qiu, Yi, Wibowo, Yohanes Cakrapradipta, Pan, Jianyuan, Wieland, Thomas, Feng, Yuxi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623831/ https://www.ncbi.nlm.nih.gov/pubmed/37923999 http://dx.doi.org/10.1186/s10020-023-00749-9 |
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