Cardioprotective function of sclerostin by reducing calcium deposition, proliferation, and apoptosis in human vascular smooth muscle cells

BACKGROUND: Sclerostin is an inhibitor of the Wnt/b-catenin pathway, which regulates bone formation, and can be expressed in vascular smooth muscle cells (VSMCs). Type 2 diabetes (T2D) is associated with an increased risk of cardiovascular disease (CVD) and increased serum and tissue expression of s...

Descripción completa

Detalles Bibliográficos
Autores principales: González-Salvatierra, Sheila, García-Fontana, Cristina, Lacal, Jesus, Andújar-Vera, Francisco, Martínez-Heredia, Luis, Sanabria-de la Torre, Raquel, Ferrer-Millán, María, Moratalla-Aranda, Enrique, Muñoz-Torres, Manuel, García-Fontana, Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623848/
https://www.ncbi.nlm.nih.gov/pubmed/37919715
http://dx.doi.org/10.1186/s12933-023-02043-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623848/
https://www.ncbi.nlm.nih.gov/pubmed/37919715
http://dx.doi.org/10.1186/s12933-023-02043-8

Ejemplares similares