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AKT1 induces Nanog promoter in a SUMOylation-dependent manner in different pluripotent contexts

AKT/PKB is a kinase crucial for pluripotency maintenance in pluripotent stem cells. Multiple post-translational modifications modulate its activity. We have previously demonstrated that AKT1 induces the expression of the pluripotency transcription factor Nanog in a SUMOylation-dependent manner in mo...

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Detalles Bibliográficos
Autores principales: Francia, Marcos Gabriel, Verneri, Paula, Oses, Camila, Vazquez Echegaray, Camila, Garcia, Mora Reneé, Toro, Ayelen, Levi, Valeria, Guberman, Alejandra Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623886/
https://www.ncbi.nlm.nih.gov/pubmed/37919788
http://dx.doi.org/10.1186/s13104-023-06598-3