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AKT1 induces Nanog promoter in a SUMOylation-dependent manner in different pluripotent contexts
AKT/PKB is a kinase crucial for pluripotency maintenance in pluripotent stem cells. Multiple post-translational modifications modulate its activity. We have previously demonstrated that AKT1 induces the expression of the pluripotency transcription factor Nanog in a SUMOylation-dependent manner in mo...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623886/ https://www.ncbi.nlm.nih.gov/pubmed/37919788 http://dx.doi.org/10.1186/s13104-023-06598-3 |