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LRH‐1 activation alleviates diabetes‐induced podocyte injury by promoting GLS2‐mediated glutaminolysis

Alteration of metabolic phenotype in podocytes directly contributes to the development of albuminuria and renal injury in conditions of diabetic kidney disease (DKD). This study aimed to identify and evaluate liver receptor homologue‐1 (LRH‐1) as a possible therapeutic target that alleviates glutami...

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Detalles Bibliográficos
Autores principales: Hu, Jijia, Zhang, Zongwei, Hu, Hongtu, Yang, Keju, Zhu, Zijing, Yang, Qian, Liang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623971/
https://www.ncbi.nlm.nih.gov/pubmed/37057309
http://dx.doi.org/10.1111/cpr.13479