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Small extracellular vesicles derived from umbilical cord mesenchymal stem cells repair blood-spinal cord barrier disruption after spinal cord injury through down-regulation of Endothelin-1 in rats

Spinal cord injury could cause irreversible neurological dysfunction by destroying the blood-spinal cord barrier (BSCB) and allowing blood cells like neutrophils and macrophages to infiltrate the spinal cord. Small extracellular vesicles (sEVs) derived from mesenchymal stem cells (MSCs) found in the...

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Detalles Bibliográficos
Autores principales: Xue, Chenhui, Ma, Xun, Guan, Xiaoming, Feng, Haoyu, Zheng, Mingkui, Yang, Xihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624166/
https://www.ncbi.nlm.nih.gov/pubmed/37927780
http://dx.doi.org/10.7717/peerj.16311