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Human dermal fibroblast subpopulations and epithelial mesenchymal transition signals in hidradenitis suppurativa tunnels are normalized by spleen tyrosine kinase antagonism in vivo

Hidradenitis Suppurativa is a chronic inflammatory disease of which the pathogenesis is incompletely understood. Dermal fibroblasts have been previously identified as a major source of inflammatory cytokines, however information pertaining to the characteristics of subpopulations of fibroblasts in H...

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Detalles Bibliográficos
Autores principales: Flora, Akshay, Jepsen, Rebecca, Kozera, Emily K., Woods, Jane A., Cains, Geoffrey D., Radzieta, Michael, Jensen, Slade O., Malone, Matthew, Frew, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624284/
https://www.ncbi.nlm.nih.gov/pubmed/37922232
http://dx.doi.org/10.1371/journal.pone.0282763