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Independent regulation of Z-lines and M-lines during sarcomere assembly in cardiac myocytes revealed by the automatic image analysis software sarcApp

Sarcomeres are the basic contractile units within cardiac myocytes, and the collective shortening of sarcomeres aligned along myofibrils generates the force driving the heartbeat. The alignment of the individual sarcomeres is important for proper force generation, and misaligned sarcomeres are assoc...

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Detalles Bibliográficos
Autores principales: Neininger-Castro, Abigail C, Hayes, James B, Sanchez, Zachary C, Taneja, Nilay, Fenix, Aidan M, Moparthi, Satish, Vassilopoulos, Stéphane, Burnette, Dylan Tyler
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624428/
https://www.ncbi.nlm.nih.gov/pubmed/37921850
http://dx.doi.org/10.7554/eLife.87065