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Exploring the Role of Plasma Lipids and Statin Interventions on Multiple Sclerosis Risk and Severity: A Mendelian Randomization Study

BACKGROUND AND OBJECTIVES: There has been considerable interest in statins because of their pleiotropic effects beyond their lipid-lowering properties. Many of these pleiotropic effects are predominantly ascribed to Rho small guanosine triphosphatases (Rho GTPases) proteins. We aimed to genetically...

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Detalles Bibliográficos
Autores principales: Almramhi, Mona M., Finan, Chris, Storm, Catherine S., Schmidt, Amand F., Kia, Demis A., Coneys, Rachel, Chopade, Sandesh, Hingorani, Aroon D., Wood, Nick W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624499/
https://www.ncbi.nlm.nih.gov/pubmed/37657941
http://dx.doi.org/10.1212/WNL.0000000000207777