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Clinical impact of the genomic landscape and leukemogenic trajectories in non-intensively treated elderly acute myeloid leukemia patients

To characterize the genomic landscape and leukemogenic pathways of older, newly diagnosed, non-intensively treated patients with AML and to study the clinical implications, comprehensive genetics analyses were performed including targeted DNA sequencing of 263 genes in 604 patients treated in a pros...

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Detalles Bibliográficos
Autores principales: Jahn, Ekaterina, Saadati, Maral, Fenaux, Pierre, Gobbi, Marco, Roboz, Gail J., Bullinger, Lars, Lutsik, Pavlo, Riedel, Anna, Plass, Christoph, Jahn, Nikolaus, Walter, Claudia, Holzmann, Karlheinz, Hao, Yong, Naim, Sue, Schreck, Nicholas, Krzykalla, Julia, Benner, Axel, Keer, Harold N., Azab, Mohammad, Döhner, Konstanze, Döhner, Hartmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624608/
https://www.ncbi.nlm.nih.gov/pubmed/37591941
http://dx.doi.org/10.1038/s41375-023-01999-6