FBXO21 mediated degradation of p85α regulates proliferation and survival of acute myeloid leukemia

Acute myeloid leukemia (AML) is a heterogeneous disease characterized by clonal expansion of myeloid blasts in the bone marrow (BM). Despite advances in therapy, the prognosis for AML patients remains poor, and there is a need to identify novel molecular pathways regulating tumor cell survival and p...

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Detalles Bibliográficos
Autores principales: Dobish, Kasidy K., Wittorf, Karli J., Swenson, Samantha A., Bean, Dalton C., Gavile, Catherine M., Woods, Nicholas T., Ghosal, Gargi, Hyde, R. Katherine, Buckley, Shannon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624613/
https://www.ncbi.nlm.nih.gov/pubmed/37689825
http://dx.doi.org/10.1038/s41375-023-02020-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624613/
https://www.ncbi.nlm.nih.gov/pubmed/37689825
http://dx.doi.org/10.1038/s41375-023-02020-w

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