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A SAM analogue-utilizing ribozyme for site-specific RNA alkylation in living cells

Post-transcriptional RNA modification methods are in high demand for site-specific RNA labelling and analysis of RNA functions. In vitro-selected ribozymes are attractive tools for RNA research and have the potential to overcome some of the limitations of chemoenzymatic approaches with repurposed me...

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Detalles Bibliográficos
Autores principales: Okuda, Takumi, Lenz, Ann-Kathrin, Seitz, Florian, Vogel, Jörg, Höbartner, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624628/
https://www.ncbi.nlm.nih.gov/pubmed/37667013
http://dx.doi.org/10.1038/s41557-023-01320-z