Ppm1d truncating mutations promote the development of genotoxic stress-induced AML

Hematopoietic stem cells (HSCs) ensure blood cell production during the life-time of an organism, and to do so they need to balance self-renewal, proliferation, differentiation, and migration in a steady state as well as in response to stress or injury. Importantly, aberrant proliferation of HSCs le...

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Detalles Bibliográficos
Autores principales: Burocziova, Monika, Danek, Petr, Oravetzova, Anna, Chalupova, Zuzana, Alberich-Jorda, Meritxell, Macurek, Libor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624630/
https://www.ncbi.nlm.nih.gov/pubmed/37709843
http://dx.doi.org/10.1038/s41375-023-02030-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624630/
https://www.ncbi.nlm.nih.gov/pubmed/37709843
http://dx.doi.org/10.1038/s41375-023-02030-8

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