Mapping protein dynamics at high spatial resolution with temperature-jump X-ray crystallography

Understanding and controlling protein motion at atomic resolution is a hallmark challenge for structural biologists and protein engineers because conformational dynamics are essential for complex functions such as enzyme catalysis and allosteric regulation. Time-resolved crystallography offers a win...

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Detalles Bibliográficos
Autores principales: Wolff, Alexander M., Nango, Eriko, Young, Iris D., Brewster, Aaron S., Kubo, Minoru, Nomura, Takashi, Sugahara, Michihiro, Owada, Shigeki, Barad, Benjamin A., Ito, Kazutaka, Bhowmick, Asmit, Carbajo, Sergio, Hino, Tomoya, Holton, James M., Im, Dohyun, O’Riordan, Lee J., Tanaka, Tomoyuki, Tanaka, Rie, Sierra, Raymond G., Yumoto, Fumiaki, Tono, Kensuke, Iwata, So, Sauter, Nicholas K., Fraser, James S., Thompson, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624634/
https://www.ncbi.nlm.nih.gov/pubmed/37723259
http://dx.doi.org/10.1038/s41557-023-01329-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624634/
https://www.ncbi.nlm.nih.gov/pubmed/37723259
http://dx.doi.org/10.1038/s41557-023-01329-4

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