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Development of mesothelioma-specific oncolytic immunotherapy enabled by immunopeptidomics of murine and human mesothelioma tumors

Malignant pleural mesothelioma (MPM) is an aggressive tumor with a poor prognosis. As the available therapeutic options show a lack of efficacy, novel therapeutic strategies are urgently needed. Given its T-cell infiltration, we hypothesized that MPM is a suitable target for therapeutic cancer vacci...

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Detalles Bibliográficos
Autores principales: Chiaro, Jacopo, Antignani, Gabriella, Feola, Sara, Feodoroff, Michaela, Martins, Beatriz, Cojoc, Hanne, Russo, Salvatore, Fusciello, Manlio, Hamdan, Firas, Ferrari, Valentina, Ciampi, Daniele, Ilonen, Ilkka, Räsänen, Jari, Mäyränpää, Mikko, Partanen, Jukka, Koskela, Satu, Honkanen, Jarno, Halonen, Jussi, Kuryk, Lukasz, Rescigno, Maria, Grönholm, Mikaela, Branca, Rui M., Lehtiö, Janne, Cerullo, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624665/
https://www.ncbi.nlm.nih.gov/pubmed/37923723
http://dx.doi.org/10.1038/s41467-023-42668-7