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To investigate the mechanism of Yiwei Decoction in the treatment of premature ovarian insufficiency-related osteoporosis using transcriptomics, network pharmacology and molecular docking techniques

To investigate the molecular mechanism of Yiwei Decoction (YWD) in preventing Premature ovarian insufficiency (POI)-related osteoporosis from the hypothalamic perspective , and to screen for the key active and acting molecules in YWD. Cyclophosphamide was used to create the POI rat model. Groups A,...

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Detalles Bibliográficos
Autores principales: Fan, Weisen, Meng, Yan, Zhang, Jing, Li, Muzhen, Zhang, Yingjie, Qu, Xintian, Xiu, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624676/
https://www.ncbi.nlm.nih.gov/pubmed/37923747
http://dx.doi.org/10.1038/s41598-023-45699-8