Quantification of rare somatic single nucleotide variants by droplet digital PCR using SuperSelective primers

Somatic single-nucleotide variants (SNVs) occur every time a cell divides, appearing even in healthy tissues at low frequencies. These mutations may accumulate as neutral variants during aging, or eventually, promote the development of neoplasia. Here, we present the SP-ddPCR, a droplet digital PCR...

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Detalles Bibliográficos
Autores principales: Pablo-Fontecha, Verónica, Hernández-Illán, Eva, Reparaz, Andrea, Asensio, Elena, Morata, Jordi, Tonda, Raúl, Lahoz, Sara, Parra, Carolina, Lozano, Juan José, García-Heredia, Anabel, Martínez-Roca, Alejandro, Beltran, Sergi, Balaguer, Francesc, Jover, Rodrigo, Castells, Antoni, Trullàs, Ramon, Podlesniy, Petar, Camps, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624686/
https://www.ncbi.nlm.nih.gov/pubmed/37923774
http://dx.doi.org/10.1038/s41598-023-39874-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624686/
https://www.ncbi.nlm.nih.gov/pubmed/37923774
http://dx.doi.org/10.1038/s41598-023-39874-0

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