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Fabrication and optimization of itraconazole-loaded zein-based nanoparticles in coated capsules as a promising colon-targeting approach pursuing opportunistic fungal infections

Itraconazole (ITZ), a broad-spectrum antifungal drug, was formulated into colon-targeting system aiming to treat opportunistic colonic fungal infections that commonly infect chronic inflammatory bowel diseases (IBD) patients due to immunosuppressive therapy. Antisolvent precipitation technique was e...

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Detalles Bibliográficos
Autores principales: Adel, Shery, Fahmy, Rania H., Elsayed, Ibrahim, Mohamed, Magdy I., Ibrahim, Reem R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624751/
https://www.ncbi.nlm.nih.gov/pubmed/37270444
http://dx.doi.org/10.1007/s13346-023-01365-0