Phosphopeptides P140 cause oxidative burst responses of pulmonary macrophages in an imiquimod-induced lupus model

Recent studies challenge the dogma that a 21-mer phosphopeptide P140 protects against direct cell damage in the phase-III clinical trial (NCT02504645) for lupus, involving reactive oxygen species (ROS)-dependent release of citrullinated histone H3 (H3cit)-linked neutrophil extracellular traps. An op...

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Detalles Bibliográficos
Autores principales: Zhong, Jianghong, Zheng, Chanyu, Chen, Zhongheng, Yue, Hangqi, Gao, Haiqiang, Jiang, Yunfan, Hui, Hui, Tian, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624795/
https://www.ncbi.nlm.nih.gov/pubmed/37922035
http://dx.doi.org/10.1186/s43556-023-00149-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624795/
https://www.ncbi.nlm.nih.gov/pubmed/37922035
http://dx.doi.org/10.1186/s43556-023-00149-9

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