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PRO-IP-seq tracks molecular modifications of engaged Pol II complexes at nucleotide resolution

RNA Polymerase II (Pol II) is a multi-subunit complex that undergoes covalent modifications as transcription proceeds through genes and enhancers. Rate-limiting steps of transcription control Pol II recruitment, site and degree of initiation, pausing duration, productive elongation, nascent transcri...

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Detalles Bibliográficos
Autores principales: Vihervaara, Anniina, Versluis, Philip, Himanen, Samu V., Lis, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624850/
https://www.ncbi.nlm.nih.gov/pubmed/37923726
http://dx.doi.org/10.1038/s41467-023-42715-3