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ADRB2 inhibition combined with antioxidant treatment alleviates lung fibrosis by attenuating TGFβ/SMAD signaling in lung fibroblasts

Idiopathic pulmonary fibrosis is a progressive and fatal interstitial lung disease with a poor prognosis and limited therapeutic options, which is characterized by aberrant myofibroblast activation and pathological remodeling of the extracellular matrix, while the mechanism remains elusive. In the p...

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Detalles Bibliográficos
Autores principales: Wan, Ruyan, Wang, Lan, Duan, Yudi, Zhu, Miaomiao, Li, Wenwen, Zhao, Mengxia, Yuan, Hongmei, Xu, Kai, Li, Zhongzheng, Zhang, Xiao, Yu, Guoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624856/
https://www.ncbi.nlm.nih.gov/pubmed/37923730
http://dx.doi.org/10.1038/s41420-023-01702-9