HLA allele-calling using multi-ancestry whole-exome sequencing from the UK Biobank identifies 129 novel associations in 11 autoimmune diseases

The human leukocyte antigen (HLA) region on chromosome 6 is strongly associated with many immune-mediated and infection-related diseases. Due to its highly polymorphic nature and complex linkage disequilibrium patterns, traditional genetic association studies of single nucleotide polymorphisms do no...

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Detalles Bibliográficos
Autores principales: Butler-Laporte, Guillaume, Farjoun, Joseph, Nakanishi, Tomoko, Lu, Tianyuan, Abner, Erik, Chen, Yiheng, Hultström, Michael, Metspalu, Andres, Milani, Lili, Mägi, Reedik, Nelis, Mari, Hudjashov, Georgi, Yoshiji, Satoshi, Ilboudo, Yann, Liang, Kevin Y. H., Su, Chen-Yang, Willet, Julian D. S., Esko, Tõnu, Zhou, Sirui, Forgetta, Vincenzo, Taliun, Daniel, Richards, J. Brent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624861/
https://www.ncbi.nlm.nih.gov/pubmed/37923823
http://dx.doi.org/10.1038/s42003-023-05496-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624861/
https://www.ncbi.nlm.nih.gov/pubmed/37923823
http://dx.doi.org/10.1038/s42003-023-05496-5

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