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Two novel phages PSPa and APPa inhibit planktonic, sessile and persister populations of Pseudomonas aeruginosa, and mitigate its virulence in Zebrafish model

The present study explores the avenue of phage therapy as an alternative antimicrobial therapeutic approach to counter multidrug-resistant (MDR) Pseudomonas aeruginosa infection. Our study investigated two novel virulent phages PSPa and APPa, specific to P. aeruginosa, in which in vitro evaluations...

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Detalles Bibliográficos
Autores principales: Karthika, Chandrasekar, Malligarjunan, Nambiraman, Jothi, Ravi, Kasthuri, Thirupathi, Alexpandi, Rajaiah, Ravi, Arumugam Veera, Pandian, Shunmugiah Karutha, Gowrishankar, Shanmugaraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624879/
https://www.ncbi.nlm.nih.gov/pubmed/37923820
http://dx.doi.org/10.1038/s41598-023-45313-x