Structural basis for the toxicity of Legionella pneumophila effector SidH

Legionella pneumophila (LP) secretes more than 300 effectors into the host cytosol to facilitate intracellular replication. One of these effectors, SidH, 253 kDa in size with no sequence similarity to proteins of known function is toxic when overexpressed in host cells. SidH is regulated by the LP m...

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Detalles Bibliográficos
Autores principales: Sharma, Rahul, Adams, Michael, Griffith-Jones, Simonne, Sahr, Tobias, Gomez-Valero, Laura, Weis, Felix, Hons, Michael, Gharbi, Sarah, Berkane, Rayene, Stolz, Alexandra, Buchrieser, Carmen, Bhogaraju, Sagar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624908/
https://www.ncbi.nlm.nih.gov/pubmed/37923743
http://dx.doi.org/10.1038/s41467-023-42683-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624908/
https://www.ncbi.nlm.nih.gov/pubmed/37923743
http://dx.doi.org/10.1038/s41467-023-42683-8

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