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Nephropathy Is Aggravated by Fatty Acids in Diabetic Kidney Disease through Tubular Epithelial Cell Necroptosis and Is Alleviated by an RIPK-1 Inhibitor

INTRODUCTION: Diabetic kidney disease (DKD), one of the leading causes of end-stage renal disease, has complex pathogenic mechanisms and few effective clinical therapies. DKD progression is accompanied by the loss of renal resident cells, followed by chronic inflammation and extracellular matrix dep...

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Detalles Bibliográficos
Autores principales: Yu, Qi, Chen, Ying, Zhao, Youlu, Huang, Shuo, Xin, Xiaohong, Jiang, Lei, Wang, Hui, Wu, Wenyan, Qu, Lei, Xiang, Chengang, Wang, Suxia, Liu, Gang, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624943/
https://www.ncbi.nlm.nih.gov/pubmed/37927402
http://dx.doi.org/10.1159/000529995