Altered calcium signaling in Bergmann glia contributes to spinocerebellar ataxia type-1 in a mouse model of SCA1

Spinocerebellar ataxia type 1 (SCA1) is a neurodegenerative disease caused by an abnormal expansion of glutamine (Q) encoding CAG repeats in the ATAXIN1 (ATXN1) gene and characterized by progressive cerebellar ataxia, dysarthria, and eventual deterioration of bulbar functions. SCA1 shows severe dege...

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Detalles Bibliográficos
Autores principales: Nanclares, Carmen, Noriega-Prieto, Jose Antonio, Labrada-Moncada, Francisco E., Cvetanovic, Marija, Araque, Alfonso, Kofuji, Paulo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624966/
https://www.ncbi.nlm.nih.gov/pubmed/37802154
http://dx.doi.org/10.1016/j.nbd.2023.106318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624966/
https://www.ncbi.nlm.nih.gov/pubmed/37802154
http://dx.doi.org/10.1016/j.nbd.2023.106318

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