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Comparative effectiveness of nirmatrelvir/ritonavir versus sotrovimab and molnupiravir for preventing severe COVID-19 outcomes in non-hospitalised high-risk patients during Omicron waves: observational cohort study using the OpenSAFELY platform

BACKGROUND: Timely evidence of the comparative effectiveness between COVID-19 therapies in real-world settings is needed to inform clinical care. This study aimed to compare the effectiveness of nirmatrelvir/ritonavir versus sotrovimab and molnupiravir in preventing severe COVID-19 outcomes in non-h...

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Detalles Bibliográficos
Autores principales: Zheng, Bang, Tazare, John, Nab, Linda, Green, Amelia CA., Curtis, Helen J., Mahalingasivam, Viyaasan, Herrett, Emily L., Costello, Ruth E., Eggo, Rosalind M., Speed, Victoria, Bacon, Sebastian CJ., Bates, Christopher, Parry, John, Cockburn, Jonathan, Hester, Frank, Harper, Sam, Schaffer, Andrea L., Hulme, William J., Mehrkar, Amir, Evans, Stephen JW., MacKenna, Brian, Goldacre, Ben, Douglas, Ian J., Tomlinson, Laurie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624988/
https://www.ncbi.nlm.nih.gov/pubmed/37927438
http://dx.doi.org/10.1016/j.lanepe.2023.100741