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Polylactide Degradation Activates Immune Cells by Metabolic Reprogramming

Polylactide (PLA) is the most widely utilized biopolymer in medicine. However, chronic inflammation and excessive fibrosis resulting from its degradation remain significant obstacles to extended clinical use. Immune cell activation has been correlated to the acidity of breakdown products, yet method...

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Detalles Bibliográficos
Autores principales: Maduka, Chima V., Alhaj, Mohammed, Ural, Evran, Habeeb, Oluwatosin M., Kuhnert, Maxwell M., Smith, Kylie, Makela, Ashley V., Pope, Hunter, Chen, Shoue, Hix, Jeremy M., Mallett, Christiane L., Chung, Seock‐Jin, Hakun, Maxwell, Tundo, Anthony, Zinn, Kurt R., Hankenson, Kurt D., Goodman, Stuart B., Narayan, Ramani, Contag, Christopher H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625072/
https://www.ncbi.nlm.nih.gov/pubmed/37737614
http://dx.doi.org/10.1002/advs.202304632