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FMRP Long-Range Transport and Degradation Are Mediated by Dynlrb1 in Sensory Neurons

The fragile X messenger ribonucleoprotein 1 (FMRP) is a multifunctional RNA-binding protein implicated in human neurodevelopmental and neurodegenerative disorders. FMRP mediates the localization and activity-dependent translation of its associated mRNAs through the formation of phase-separated conde...

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Detalles Bibliográficos
Autores principales: El-Agamy, Sara Emad, Guillaud, Laurent, Kono, Keiko, Wu, Yibo, Terenzio, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625159/
https://www.ncbi.nlm.nih.gov/pubmed/37739344
http://dx.doi.org/10.1016/j.mcpro.2023.100653