Advanced glycation end products impair bone marrow mesenchymal stem cells osteogenesis in periodontitis with diabetes via FTO-mediated N(6)-methyladenosine modification of sclerostin

BACKGROUND: Diabetes mellitus (DM) and periodontitis are two prevalent diseases with mutual influence. Accumulation of advanced glycation end products (AGEs) in hyperglycemia may impair cell function and worsen periodontal conditions. N(6)-methyladenosine (m(6)A) is an important post-transcriptional...

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Detalles Bibliográficos
Autores principales: Zhou, Jie, Zhu, Yanlin, Ai, Dongqing, Zhou, Mengjiao, Li, Han, Li, Guangyue, Zheng, Leilei, Song, Jinlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625275/
https://www.ncbi.nlm.nih.gov/pubmed/37925419
http://dx.doi.org/10.1186/s12967-023-04630-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625275/
https://www.ncbi.nlm.nih.gov/pubmed/37925419
http://dx.doi.org/10.1186/s12967-023-04630-5

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