Cargando…

sFgl2 gene-modified MSCs regulate the differentiation of CD4(+) T cells in the treatment of autoimmune hepatitis

BACKGROUND: Autoimmune hepatitis (AIH) is a T-cell-mediated autoimmune liver disease that can lead to liver injury and has a poor long-term prognosis. Mesenchymal stromal cells (MSCs) have immunosuppressive effects and can treat AIH. CD4(+) T cells express the unique inhibitory Fcγ receptor (FcγRIIB...

Descripción completa

Detalles Bibliográficos
Autores principales: Ji, Wenbin, Wang, Weiwei, Li, Peiyuan, Liu, Yanhong, Zhang, Baotong, Qi, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625288/
https://www.ncbi.nlm.nih.gov/pubmed/37924141
http://dx.doi.org/10.1186/s13287-023-03550-x