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sFgl2 gene-modified MSCs regulate the differentiation of CD4(+) T cells in the treatment of autoimmune hepatitis
BACKGROUND: Autoimmune hepatitis (AIH) is a T-cell-mediated autoimmune liver disease that can lead to liver injury and has a poor long-term prognosis. Mesenchymal stromal cells (MSCs) have immunosuppressive effects and can treat AIH. CD4(+) T cells express the unique inhibitory Fcγ receptor (FcγRIIB...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625288/ https://www.ncbi.nlm.nih.gov/pubmed/37924141 http://dx.doi.org/10.1186/s13287-023-03550-x |