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Improving efficiency of fitting Cox proportional hazards models for time-to-event outcomes in genome-wide association studies (GWAS)

SUMMARY: Technologies identifying single nucleotide polymorphisms (SNPs) in DNA sequencing yield an avalanche of data requiring analysis and interpretation. Standard methods may require many weeks of processing time. The use of statistical methods requiring data sorting, matrix inversions of a high-...

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Detalles Bibliográficos
Autores principales: Gebski, Val, Silva, S Sandun M, Byth, Karen, Jenkins, Alicia, Keech, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625458/
https://www.ncbi.nlm.nih.gov/pubmed/37928342
http://dx.doi.org/10.1093/bioadv/vbad148