Systemic and intrinsic functions of ATRX in glial cell fate and CNS myelination in male mice

Myelin, an extension of the oligodendrocyte plasma membrane, wraps around axons to facilitate nerve conduction. Myelination is compromised in ATR-X intellectual disability syndrome patients, but the causes are unknown. We show that loss of ATRX leads to myelination deficits in male mice that are par...

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Detalles Bibliográficos
Autores principales: Rowland, Megan E., Jiang, Yan, Shafiq, Sarfraz, Ghahramani, Alireza, Pena-Ortiz, Miguel A., Dumeaux, Vanessa, Bérubé, Nathalie G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625541/
https://www.ncbi.nlm.nih.gov/pubmed/37925436
http://dx.doi.org/10.1038/s41467-023-42752-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625541/
https://www.ncbi.nlm.nih.gov/pubmed/37925436
http://dx.doi.org/10.1038/s41467-023-42752-y

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