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Systemic and intrinsic functions of ATRX in glial cell fate and CNS myelination in male mice
Myelin, an extension of the oligodendrocyte plasma membrane, wraps around axons to facilitate nerve conduction. Myelination is compromised in ATR-X intellectual disability syndrome patients, but the causes are unknown. We show that loss of ATRX leads to myelination deficits in male mice that are par...
Autores principales: | Rowland, Megan E., Jiang, Yan, Shafiq, Sarfraz, Ghahramani, Alireza, Pena-Ortiz, Miguel A., Dumeaux, Vanessa, Bérubé, Nathalie G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625541/ https://www.ncbi.nlm.nih.gov/pubmed/37925436 http://dx.doi.org/10.1038/s41467-023-42752-y |
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