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Absence of the primary cilia formation gene Talpid3 impairs muscle stem cell function

Skeletal muscle stem cells (MuSC) are crucial for tissue homoeostasis and repair after injury. Following activation, they proliferate to generate differentiating myoblasts. A proportion of cells self-renew, re-enter the MuSC niche under the basal lamina outside the myofiber and become quiescent. Qui...

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Detalles Bibliográficos
Autores principales: Martinez-Heredia, Victor, Blackwell, Danielle, Sebastian, Sujith, Pearson, Timothy, Mok, Gi Fay, Mincarelli, Laura, Utting, Charlotte, Folkes, Leighton, Poeschl, Ernst, Macaulay, Iain, Mayer, Ulrike, Münsterberg, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625638/
https://www.ncbi.nlm.nih.gov/pubmed/37925530
http://dx.doi.org/10.1038/s42003-023-05503-9