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eRNA co-expression network uncovers TF dependency and convergent cooperativity

Enhancer RNAs (eRNAs) are non-coding RNAs produced by transcriptional enhancers that are highly correlated with their activity. Using a capped nascent RNA sequencing (PRO-cap) dataset in human lymphoblastoid cell lines across 67 individuals, we identified inter-individual variation in the expression...

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Detalles Bibliográficos
Autores principales: Lee, Seungha Alisa, Kristjánsdóttir, Katla, Kwak, Hojoong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625640/
https://www.ncbi.nlm.nih.gov/pubmed/37925545
http://dx.doi.org/10.1038/s41598-023-46415-2