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Deep neural network based tissue deconvolution of circulating tumor cell RNA

Prior research has shown that the deconvolution of cell-free RNA can uncover the tissue origin. The conventional deconvolution approaches rely on constructing a reference tissue-specific gene panel, which cannot capture the inherent variation present in actual data. To address this, we have develope...

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Detalles Bibliográficos
Autores principales: Yan, Fengyao, Jiang, Limin, Ye, Fei, Ping, Jie, Bowley, Tetiana Y., Ness, Scott A., Li, Chung-I, Marchetti, Dario, Tang, Jijun, Guo, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625696/
https://www.ncbi.nlm.nih.gov/pubmed/37925448
http://dx.doi.org/10.1186/s12967-023-04663-w