Synergistic Effects of Azithromycin and STING Agonist Promote IFN-I Production by Enhancing the Activation of STING-TBK1 Signaling

BACKGROUND: Azithromycin (AZM) is a macrolide antibiotic that exhibits anti-inflammatory and anti-viral infection properties by enhancing type-I interferon (IFN-I) responses. The stimulator of interferon genes (STING) can directly induce IFN-I production. However, elevated IFN-I induces auto-immune...

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Detalles Bibliográficos
Autores principales: Petcharat, Kanoktip, Munkong, Narongsuk, Thongboontho, Rungthip, Chartarrayawadee, Widsanusan, Thim-Uam, Arthid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625772/
https://www.ncbi.nlm.nih.gov/pubmed/37933302
http://dx.doi.org/10.2147/JEP.S433181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625772/
https://www.ncbi.nlm.nih.gov/pubmed/37933302
http://dx.doi.org/10.2147/JEP.S433181

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