Antioxidants restore store‐operated Ca(2+) entry in patient‐iPSC‐derived myotubes with tubular aggregate myopathy‐associated Ile484ArgfsX21 STIM1 mutation via upregulation of binding immunoglobulin protein

Store‐operated Ca(2+) entry (SOCE) is indispensable for intracellular Ca(2+) homeostasis in skeletal muscle, and constitutive activation of SOCE causes tubular aggregate myopathy (TAM). To understand the pathogenesis of TAM, we induced pluripotent stem cells (iPSCs) from a TAM patient with a rare mu...

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Detalles Bibliográficos
Autores principales: Sakai‐Takemura, Fusako, Saito, Fumiaki, Nogami, Ken'ichiro, Maruyama, Yusuke, Elhussieny, Ahmed, Matsumura, Kiichiro, Takeda, Shin'ichi, Aoki, Yoshitsugu, Miyagoe‐Suzuki, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626159/
https://www.ncbi.nlm.nih.gov/pubmed/37936920
http://dx.doi.org/10.1096/fba.2023-00069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626159/
https://www.ncbi.nlm.nih.gov/pubmed/37936920
http://dx.doi.org/10.1096/fba.2023-00069

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