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Innate immune signaling in hearts and buccal mucosa cells of patients with arrhythmogenic cardiomyopathy

BACKGROUND: Nuclear factor κB (NF-κB) signaling in cardiac myocytes causes disease in a mouse model of arrhythmogenic cardiomyopathy (ACM) by mobilizing CCR2-expressing macrophages that promote myocardial injury and arrhythmias. Buccal mucosa cells exhibit pathologic features similar to those seen i...

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Detalles Bibliográficos
Autores principales: Bueno-Beti, Carlos, Tafuni, Alessandro, Chelko, Stephen P., Sheppard, Mary N., Field, Ella, Tollit, Jennifer, Heenan, Imogen K., Barnes, Annabelle, Taylor, Matthew R., Mestroni, Luisa, Kaski, Juan Pablo, Saffitz, Jeffrey E., Asimaki, Angeliki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626188/
https://www.ncbi.nlm.nih.gov/pubmed/37936669
http://dx.doi.org/10.1016/j.hroo.2023.09.006