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A robust pipeline for high-content, high-throughput immunophenotyping reveals age- and genetics-dependent changes in blood leukocytes

High-dimensional flow cytometry is the gold standard to study the human immune system in large cohorts. However, large sample sizes increase inter-experimental variation because of technical and experimental inaccuracies introduced by batch variability. Our high-throughput sample processing pipeline...

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Detalles Bibliográficos
Autores principales: Liechti, Thomas, Van Gassen, Sofie, Beddall, Margaret, Ballard, Reid, Iftikhar, Yaser, Du, Renguang, Venkataraman, Thiagarajan, Novak, David, Mangino, Massimo, Perfetto, Stephen, Larman, H. Benjamin, Spector, Tim, Saeys, Yvan, Roederer, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626267/
https://www.ncbi.nlm.nih.gov/pubmed/37883924
http://dx.doi.org/10.1016/j.crmeth.2023.100619