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Effects of truncations in the N‐ and C‐terminal domains of filensin on filament formation with phakinin in cell‐free conditions and cultured cells

Filensin and phakinin are lens fiber cell‐specific proteins that constitute the beaded filaments (BFs) that are critical for maintaining lens transparency. In the Shumiya cataract rat, filensin 94 kDa undergoes N‐ and C‐terminal proteolytic processing to give a transient 50 kDa fragment and a final...

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Detalles Bibliográficos
Autores principales: Tashiro, Moe, Nakamura, Akari, Kuratani, Yamato, Takada, Miyako, Iwamoto, Satoshi, Oka, Mikako, Ando, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626283/
https://www.ncbi.nlm.nih.gov/pubmed/37615966
http://dx.doi.org/10.1002/2211-5463.13700