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Predictive IDH Genotyping Based on the Evaluation of Spatial Metabolic Heterogeneity by Compartmental Uptake Characteristics in Preoperative Glioma Using (18)F-FET PET

Molecular markers are of increasing importance for classifying, treating, and determining the prognosis for central nervous system tumors. Isocitrate dehydrogenase (IDH) is a critical regulator of glucose and amino acid metabolism. Our objective was to investigate metabolic reprogramming of glioma u...

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Detalles Bibliográficos
Autores principales: Lohmeier, Johannes, Radbruch, Helena, Brenner, Winfried, Hamm, Bernd, Tietze, Anna, Makowski, Marcus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Nuclear Medicine 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626372/
https://www.ncbi.nlm.nih.gov/pubmed/37652542
http://dx.doi.org/10.2967/jnumed.123.265642